💡 A pro-grade antioxidant face serum from CIRCADIA built around plant meristem cell technology — formulated for clients showing visible signs of aging, elasticity loss, or chronic dullness.

The formula pairs Apple Stem Cell Extract (delivered via liposomal system for sustained surface contact) with Edelweiss Meristem Cell Culture, which works to inhibit the enzymes that degrade hyaluronic acid and collagen — helping skin hold onto its plumpness and smoothness over time. Cyclopeptide-5 targets integrin-mediated pathways to visibly improve firmness and reduce wrinkle depth, while Ectoin adds a stress-protective, humectant layer against UV and pollution damage.

✨ In-service, this lightweight serum absorbs fast, sits cleanly under moisturizer or SPF, and integrates into microcurrent or ultrasound protocols as a pre-treatment step — making it a versatile fit for advanced facial workflows.

Stock it when your anti-aging menu needs a serum that pulls clinical-grade actives into an everyday client protocol.

• Visible Reduction in Signs of Aging: Apple Stem Cell Extract and Edelweiss Meristem Cell Culture work together to help the skin's surface appear more youthful and vital, supporting a visible reduction in the appearance of fine lines and the dullness associated with chronological aging.
• Improved Appearance of Firmness and Elasticity: Cyclotetrapeptide-24 Aminocyclohexane Carboxylate targets integrin-mediated pathways associated with the extracellular matrix, helping the skin appear firmer, more elastic, and more resistant to visible sagging over time.
• Antioxidant Protection: Leontopodium Alpinum Meristem Cell Culture and Ectoin together provide a dual layer of antioxidant defense, helping to shield the skin's surface from the visible effects of environmental stressors such as UV exposure and pollution.
• Support for Skin's Natural Hyaluronic Acid and Collagen Appearance: Edelweiss Meristem Cell Culture Extract helps inhibit hyaluronidase and collagenase — enzymes that degrade hyaluronic acid and collagen — helping the skin maintain a plumper, more cushioned, and smoother surface appearance.
• Brightening and Revitalization of Dull Skin: The serum's plant stem cell actives help restore the appearance of radiance and clarity to dull or tired-looking skin, supporting a more luminous and even complexion tone with consistent use.

Malus Domestica Fruit Cell Culture Extract - known as Apple Stem Cell Extract: A liposomal preparation derived from the cultured stem cells of a rare Swiss apple variety, incorporated for its ability to help support the appearance of skin vitality and to visibly reduce signs of chronological aging. Delivered via a lecithin-based liposomal system, which facilitates absorption into the skin surface for sustained contact with the upper skin layers.

Leontopodium Alpinum Meristem Cell Culture - known as Edelweiss Meristem Cell Culture Extract: A preparation of cultured meristem cells from Edelweiss (Leontopodium alpinum), a plant known for surviving extreme environmental stress at high altitudes. This extract provides antioxidant activity and helps inhibit enzymes that break down the skin's hyaluronic acid and collagen, supporting a plumper, smoother skin appearance. Supplier efficacy studies indicate a visible reduction in wrinkle depth around the eye area after 20 days of regular use.

Cyclotetrapeptide-24 Aminocyclohexane Carboxylate: A novel synthetic cyclopeptide, commercially known as Cyclopeptide-5, designed to bind integrin receptors on the skin surface and support signaling pathways associated with the extracellular matrix. This action promotes the appearance of firmer, more resilient skin and contributes to a visible reduction in wrinkle depth and surface smoothness over time.

Ectoin: A naturally derived amino acid derivative (extremolyte) originally found in microorganisms that thrive under extreme conditions. In leave-on skin formulations, Ectoin acts as a powerful humectant and cellular stress protector — it stabilizes skin proteins and lipids against environmental stressors such as UV radiation and pollution, helping to maintain the skin's natural moisture balance and support a resilient, healthy-looking complexion.

1. Cleanse and prepare the client's face thoroughly before application.
2. Dispense several drops of the serum onto clean fingertips.
3. Smooth the serum evenly over the face and neck, using gentle upward strokes.
4. Allow the serum to absorb fully before applying additional products such as moisturizer or SPF.
5. Use morning and evening as part of the client's regular treatment protocol.

Layering and service integration

This serum is formulated as a lightweight, fast-absorbing step and is designed to sit beneath moisturizers and SPF products. In a professional facial service, apply immediately after exfoliation or treatment steps (such as enzyme or mild chemical exfoliation) and before occlusive or barrier-repair products — this sequencing maximizes surface contact time for the trace-effective meristem and cyclopeptide actives. For clients with significant elasticity concerns or advanced visible aging, pairing with a microcurrent or ultrasound service may support product penetration into the upper skin layers; position the serum as the conductive medium or pre-treatment serum where appropriate to your device protocol.